HitPredict

Interactor 1: ABL1 (P00519)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: ABR (Q12979)
Active breakpoint cluster region-related protein
Gene: ABR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2~SH2, RhoGEF~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 859
+	Hs
		337325 ABL1_HUMAN (1-1130): 0: 984: 100.00		BCR_HUMAN (29-859): 3.52e-174: 539: 67.86
+	Hs
		337333 ABL1_HUMAN (1-1130): 0: 984: 100.00		VAV_HUMAN (32-581): 2.81e-72: 256: 13.74
+	Hs
		337603 ABL1_HUMAN (1-1130): 0: 984: 100.00		3BP1_HUMAN (644-835): 3.18e-22: 104: 32.29
+	Hs
		506538 FRK_HUMAN (31-511): 1.18e-176: 529: 39.80		BCR_HUMAN (29-859): 3.52e-174: 539: 67.86
+	Hs
		442768 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		BCR_HUMAN (29-859): 3.52e-174: 539: 67.86
+	Hs
		64648 SRC_HUMAN (13-510): 0: 547: 38.58		RHG32_HUMAN (554-846): 4.88e-72: 261: 26.85
+	Hs
		64642 FYN_HUMAN (18-510): 0: 543: 38.64		RHG32_HUMAN (554-846): 4.88e-72: 261: 26.85
+	Hs
		412357 FYN_HUMAN (18-510): 0: 543: 38.64		ECT2_HUMAN (38-475): 3.19e-73: 260: 20.29
+	Hs
		147859 FYN_HUMAN (18-510): 0: 543: 38.64		RHG33_HUMAN (552-848): 9.61e-72: 259: 25.47
+	Hs
		411981 FYN_HUMAN (18-510): 0: 543: 38.64		VAV_HUMAN (32-581): 2.81e-72: 256: 13.74
+	Mm
		763398 FYN_MOUSE (18-510): 0: 542: 38.64		RHG33_MOUSE (552-848): 3.17e-70: 255: 25.47
+	Hs
		64641 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		RHG32_HUMAN (554-846): 4.88e-72: 261: 26.85
+	Hs
		411580 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		VAV_HUMAN (32-581): 2.81e-72: 256: 13.74
+	Hs
		224699 FYN_HUMAN (18-510): 0: 543: 38.64		KALRN_HUMAN (2-666): 1.32e-64: 239: 13.37
+	Hs
		411673 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		FGD1_HUMAN (1-554): 4.58e-70: 251: 15.21
+	Hs
		411755 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		RHG21_HUMAN (627-847): 6.65e-68: 248: 34.22
+	Hs
		224698 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		KALRN_HUMAN (2-666): 1.32e-64: 239: 13.37
+	Hs
		279830 LCK_HUMAN (9-508): 3.02e-177: 531: 38.49		TRIO_HUMAN (58-623): 1.61e-59: 223: 12.91
+	Hs
		523225 SRC_HUMAN (13-510): 0: 547: 38.58		3BP1_HUMAN (644-835): 3.18e-22: 104: 32.29
+	Hs
		442896 HCK_HUMAN (9-508): 5.18e-175: 526: 38.79		3BP1_HUMAN (644-835): 3.18e-22: 104: 32.29