HitPredict

Interactor 1: ABL1 (P00520)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: ENAH (Q03173)
Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1)
Gene: ENAH

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8861907
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0005829 - cytosol GO:0015629 - actin cytoskeleton GO:0017124 - SH3 domain binding GO:0030036 - actin cytoskeleton organization and 1 others more... GO:0043005 - neuron projection
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1123 Mm			1 802
+	Hs
		337335 ABL1_HUMAN (1-1123): 0: 925: 85.88		MUC1_HUMAN (177-802): 4.78e-31: 133: 14.13
+	Hs
		337581 ABL1_HUMAN (1-1123): 0: 925: 85.88		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Mm
		403433 SRC_MOUSE (32-510): 1.48e-179: 537: 39.84		ENAH_MOUSE (1-802): 1.66e-73: 257: 100.00
+	Mm
		763387 FYN_MOUSE (44-510): 8.2e-178: 533: 40.76		ENAH_MOUSE (1-802): 1.66e-73: 257: 100.00
+	Hs
		412242 FYN_HUMAN (44-510): 5.28e-178: 534: 40.76		SPRE1_HUMAN (2-278): 1.23e-48: 180: 19.61
+	Dm
		337658 ABL_DROME (38-1073): 0: 582: 38.33		ENA_DROME (2-171): 3.54e-29: 126: 50.57
+	Hs
		433858 LYN_HUMAN (9-508): 1.69e-168: 508: 36.15		SPRE1_HUMAN (2-278): 1.23e-48: 180: 19.61
+	Hs
		522749 SRC_HUMAN (36-510): 0: 541: 39.96		MUC1_HUMAN (177-802): 4.78e-31: 133: 14.13
+	Hs
		523190 SRC_HUMAN (36-510): 0: 541: 39.96		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Hs
		411582 LCK_HUMAN (9-508): 1.6e-174: 524: 38.49		MUC1_HUMAN (177-802): 4.78e-31: 133: 14.13
+	Hs
		442892 HCK_HUMAN (9-508): 1.52e-173: 522: 38.60		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Hs
		411790 LCK_HUMAN (9-508): 1.6e-174: 524: 38.49		MINK1_HUMAN (94-792): 1.24e-29: 128: 14.61
+	Ce
		106631 SRC1_CAEEL (9-508): 2.45e-159: 485: 36.75		G5EG53_CAEEL (2-410): 7.91e-41: 158: 15.13
+	Hs
		433560 LYN_HUMAN (9-508): 1.69e-168: 508: 36.15		MUC1_HUMAN (177-802): 4.78e-31: 133: 14.13
+	Hs
		434062 LYN_HUMAN (9-508): 1.69e-168: 508: 36.15		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Hs
		433891 LYN_HUMAN (9-508): 1.69e-168: 508: 36.15		MINK1_HUMAN (94-792): 1.24e-29: 128: 14.61
+	Ce
		106638 SRC1_CAEEL (9-508): 2.45e-159: 485: 36.75		H2L0C7_CAEEL (14-186): 3e-37: 143: 24.02
+	Hs
		297808 LYN_HUMAN (9-508): 1.69e-168: 508: 36.15		K0754_HUMAN (358-802): 1.57e-26: 119: 12.91