HitPredict

Interactor 1: ABL1 (P00520)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: DOK3 (Q9QZK7)
Docking protein 3 (Downstream of tyrosine kinase 3) (p62(dok)-like protein) (DOK-L)
Gene: DOK3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10567556
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1123 Mm			1 444
+	Mm
		337623 ABL1_MOUSE (1-1123): 0: 973: 100.00		DOK1_MOUSE (4-400): 4.54e-122: 365: 30.92
+	Mm
		250948 ABL1_MOUSE (1-1123): 0: 973: 100.00		DOK2_MOUSE (5-419): 6.51e-108: 326: 30.77
+	Hs
		337542 ABL1_HUMAN (1-1123): 0: 925: 85.88		DOK1_HUMAN (4-400): 2.57e-119: 358: 33.58
+	Hs
		235031 ABL1_HUMAN (1-1123): 0: 925: 85.88		DOK2_HUMAN (5-419): 2.4e-106: 323: 30.95
+	Hs
		789086 ABL2_HUMAN (11-1123): 0: 775: 50.90		DOK1_HUMAN (4-400): 2.57e-119: 358: 33.58
+	Hs
		433460 YES_HUMAN (5-510): 0: 542: 39.42		DOK1_HUMAN (4-400): 2.57e-119: 358: 33.58
+	Hs
		523124 SRC_HUMAN (36-510): 0: 541: 39.96		DOK1_HUMAN (4-400): 2.57e-119: 358: 33.58
+	Hs
		996570 ITK_HUMAN (44-499): 4.44e-175: 529: 35.50		DOK1_HUMAN (4-400): 2.57e-119: 358: 33.58
+	Hs
		442876 HCK_HUMAN (9-508): 1.52e-173: 522: 38.60		DOK1_HUMAN (4-400): 2.57e-119: 358: 33.58
+	Hs
		235037 YES_HUMAN (5-510): 0: 542: 39.42		DOK2_HUMAN (5-419): 2.4e-106: 323: 30.95
+	Hs
		235040 SRC_HUMAN (36-510): 0: 541: 39.96		DOK2_HUMAN (5-419): 2.4e-106: 323: 30.95
+	Mm
		250949 SRC_MOUSE (32-510): 1.48e-179: 537: 39.84		DOK2_MOUSE (5-419): 6.51e-108: 326: 30.77
+	Hs
		235036 FYN_HUMAN (44-510): 5.28e-178: 534: 40.76		DOK2_HUMAN (5-419): 2.4e-106: 323: 30.95
+	Hs
		235035 LCK_HUMAN (9-508): 1.6e-174: 524: 38.49		DOK2_HUMAN (5-419): 2.4e-106: 323: 30.95
+	Hs
		412057 FYN_HUMAN (44-510): 5.28e-178: 534: 40.76		IRS1_HUMAN (9-366): 3.64e-83: 279: 14.47
+	Hs
		151689 LCK_HUMAN (9-508): 1.6e-174: 524: 38.49		IRS4_HUMAN (9-362): 3.84e-81: 274: 15.97
+	Mm
		403453 SRC_MOUSE (32-510): 1.48e-179: 537: 39.84		FRS2_MOUSE (142-438): 1.04e-68: 228: 18.58
+	Hs
		411805 LCK_HUMAN (9-508): 1.6e-174: 524: 38.49		FRS2_HUMAN (142-439): 6.12e-70: 231: 18.52
+	Dm
		1360394 SRC42_DROME (10-508): 4.13e-174: 523: 39.22		Q9W3R6_DROME (4-256): 2.26e-63: 217: 24.23
+	Hs
		207290 HCK_HUMAN (9-508): 1.52e-173: 522: 38.60		FRS3_HUMAN (142-398): 5.31e-55: 192: 22.34