Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.71 | 1.00 | 0.845 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24658140, 35384245, unassigned2173 |
| Identification Methods | protein complementation assay, proximity labelling technology, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FERM_M~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0005768 - endosome GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 10 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
