HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: EMD (P50402)
Emerin
Gene: EMD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	24797263, 28065597, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0031965 - nuclear membrane GO:0045296 - cadherin binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 254
+	Hs
		383696 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		EMD_HUMAN (1-254): 1.32e-153: 429: 100.00
+	Hs
		601855 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		EMD_HUMAN (1-254): 1.32e-153: 429: 100.00
+	Hs
		434161 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		EMD_HUMAN (1-254): 1.32e-153: 429: 100.00
+	Hs
		411336 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		EMD_HUMAN (1-254): 1.32e-153: 429: 100.00
+	Hs
		537726 INSRR_HUMAN (352-656): 3.99e-25: 115: 20.90		EMD_HUMAN (1-254): 1.32e-153: 429: 100.00
+	Hs
		435587 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		EMD_HUMAN (1-254): 1.32e-153: 429: 100.00