Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 22366308, 31980649, unassigned2173
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 6 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 375
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+ Rn

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Last updated: 15 Jul 2024