Protein: NIP7
60S ribosome subunit biogenesis protein NIP7 (Nuclear import protein 7)

Gene: NIP7
Organism: Saccharomyces cerevisiae S288C
Interactions: 133
UniProt ID: Q08962

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

830205

NOP2
25S rRNA

7

3

Small-scale

0.963

High

1065572

MAK21
Ribosome biogenesis protein MAK21

3

3

High-throughput

0.855

High

818292

NSA2
Ribosome biogenesis protein NSA2

2

1

High-throughput

0.793

High

782479

RPF2
Ribosome biogenesis protein RPF2

8

0

Small-scale

0.713

High

919034

PESC
Pescadillo homolog

7

0

Small-scale

0.709

High

1062929

NOP8
60S ribosome subunit biogenesis protein NOP8

5

0

Small-scale

0.687

High

682413

SPB4
ATP-dependent rRNA helicase SPB4

4

2

High-throughput

0.686

High

1039652

NOG1
Nucleolar GTP-binding protein 1

4

1

Small-scale

0.686

High

804683

SSF1
Ribosome biogenesis protein SSF1

4

2

Small-scale

0.678

High

803962

CIC1
Proteasome-interacting protein CIC1

3

2

High-throughput

0.656

High

816926

NUG1
Nuclear GTP-binding protein NUG1

3

1

Small-scale

0.656

High

917580

NSA1
Ribosome biogenesis protein NSA1

3

1

Small-scale

0.656

High

1043308

HAS1
ATP-dependent RNA helicase HAS1

3

2

High-throughput

0.656

High

1062787

BRX1
Ribosome biogenesis protein BRX1

3

7

Small-scale

0.656

High

1065568

YTM1
Ribosome biogenesis protein YTM1

3

1

Small-scale

0.656

High

672974

RRP43
Exosome complex component RRP43

3

0

Small-scale

0.648

High

827631

RLP7
Ribosome biogenesis protein RLP7

3

2

Small-scale

0.640

High

850033

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

High-throughput

0.622

High

925454

RCM1
25S rRNA

1

3

High-throughput

0.618

High

1055511

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.618

High

1060746

NOC3
Nucleolar complex-associated protein 3

1

2

High-throughput

0.618

High

1065569

NOP53
Ribosome biogenesis protein NOP53

3

0

Small-scale

0.614

High

1065573

RL7B
Large ribosomal subunit protein uL30B

2

2

High-throughput

0.611

High

806673

RIX1
Pre-rRNA-processing protein RIX1

2

0

High-throughput

0.585

High

924346

NOP13
Nucleolar protein 13

2

0

High-throughput

0.585

High

1046533

PUF6
Pumilio homology domain family member 6

2

0

High-throughput

0.585

High

633203

MAK11
Protein MAK11

2

1

Small-scale

0.584

High

763135

RRP1
Ribosomal RNA-processing protein 1

2

2

Small-scale

0.584

High

924864

NOP15
Ribosome biogenesis protein 15

2

2

High-throughput

0.584

High

805109

RPF1
Ribosome production factor 1

2

1

High-throughput

0.571

High

1064854

RRS1
Regulator of ribosome biosynthesis

2

2

High-throughput

0.571

High

814411

NOC2
Nucleolar complex protein 2

2

0

Small-scale

0.559

High

1044912

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

1065575

DBP10
ATP-dependent RNA helicase DBP10

2

0

High-throughput

0.559

High

1060855

SDO1
Ribosome maturation protein SDO1

1

0

Small-scale

0.549

High

712686

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.536

High

743308

PP12
Serine/threonine-protein phosphatase PP1-2

1

1

High-throughput

0.536

High

546613

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

513268

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.517

High

568939

INO4
Protein INO4

1

0

High-throughput

0.513

High

684873

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

923146

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

1030599

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

1044236

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.513

High

1060417

RIX7
Ribosome biogenesis ATPase RIX7

1

0

High-throughput

0.513

High

1064361

DIA2
Protein DIA2

1

0

High-throughput

0.513

High

512700

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

534160

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

677256

SPB1
27S pre-rRNA

1

1

High-throughput

0.479

High

708444

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

708799

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

745905

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

746689

DRS1
ATP-dependent RNA helicase DRS1

1

1

High-throughput

0.479

High

750166

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.479

High

752844

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

780340

EBP2
rRNA-processing protein EBP2

1

1

High-throughput

0.479

High

781665

DBP7
ATP-dependent RNA helicase DBP7

1

2

Small-scale

0.479

High

791128

NOP4
Nucleolar protein 4

1

1

High-throughput

0.479

High

807170

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

923221

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.479

High

925115

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

1047299

ERB1
Ribosome biogenesis protein ERB1

1

2

High-throughput

0.479

High

1054264

FKBP4
FK506-binding protein 4

1

1

High-throughput

0.479

High

1054374

JIP5
WD repeat-containing protein JIP5

1

1

High-throughput

0.479

High

1054410

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.479

High

1060832

RLP24
Ribosome biogenesis protein RLP24

1

1

High-throughput

0.479

High

1062347

NOP12
Nucleolar protein 12

1

2

High-throughput

0.479

High

1065570

SSF2
Ribosome biogenesis protein SSF2

1

2

High-throughput

0.479

High

1065574

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

410379

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

435416

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

442153

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

513423

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.458

High

580203

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

645007

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

674879

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

735210

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

740025

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.458

High

758268

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

780721

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

795856

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

802430

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

815267

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

816810

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

825397

BMT5
25S rRNA

1

0

High-throughput

0.458

High

826102

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

826907

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

844653

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

850239

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

864543

MTR4
ATP-dependent RNA helicase DOB1

1

0

Small-scale

0.458

High

865771

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

897520

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

1044817

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1046076

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

1046126

RRB1
Ribosome assembly protein RRB1

1

0

High-throughput

0.458

High

1050199

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

1055481

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

1059392

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

1064275

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1064810

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

1065567

MDN1
Midasin

1

0

High-throughput

0.458

High

1065571

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1065576

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

386899

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

427472

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

486343

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.445

High

525438

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527926

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

531917

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

742599

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

924070

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

365216

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

394981

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

592554

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

671733

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

676992

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.426

High

810780

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

836941

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

912466

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

734225

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

813615

ERP2
Protein ERP2

2

0

High-throughput

0.307

High

1050612

RCH1
Solute carrier RCH1

1

0

High-throughput

0.269

Low

734532

MSB2
Signaling mucin MSB2

1

0

High-throughput

0.265

Low

503860

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

554977

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

595010

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

624820

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

753634

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

802056

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.249

Low

812736

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

918484

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

575536

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

858087

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025