HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

The method score is based on:

Property	Details
Experiments	23956138, 15657067
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006412 - translation and 5 others more... GO:0016020 - membrane GO:0019900 - kinase binding GO:0019901 - protein kinase binding GO:0032587 - ruffle membrane GO:0071364 - cellular response to epidermal growth factor stimulus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	1210
Hs

1	462

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024