Protein: PLPR2
Phospholipid phosphatase-related protein type 2 (Inactive phospholipid phosphatase PLPPR2) (Lipid phosphate phosphatase-related protein type 2) (Plasticity-related gene 4 protein) (PRG-4)

Gene: PLPR2, PLPPR2
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q96GM1

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006644 - phospholipid metabolic process
GO:0007165 - signal transduction
GO:0008195 - phosphatidate phosphatase activity
GO:0046839 - phospholipid dephosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897065

MAP2
Methionine aminopeptidase 2

3

1

High-throughput

0.667

High

1015087

ARF5
ADP-ribosylation factor 5

3

1

High-throughput

0.667

High

1392025

NDK7
Nucleoside diphosphate kinase homolog 7

3

0

High-throughput

0.638

High

1392027

EPN1
Epsin-1

3

0

High-throughput

0.638

High

921389

MAP11
Methionine aminopeptidase 1

3

1

High-throughput

0.609

High

1287280

DPP9
Dipeptidyl peptidase 9

3

1

High-throughput

0.609

High

1392007

YTHD1
YTH domain-containing family protein 1

3

1

High-throughput

0.609

High

1392020

DJC12
DnaJ homolog subfamily C member 12

3

1

High-throughput

0.609

High

1392026

SAR1B
Small COPII coat GTPase SAR1B

3

3

High-throughput

0.609

High

138573

CLD5
Claudin-5

2

1

High-throughput

0.606

High

420068

GLPC
Glycophorin-C

2

1

High-throughput

0.606

High

850847

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

1

High-throughput

0.606

High

1391999

SIG12
Sialic acid-binding Ig-like lectin 12

2

2

High-throughput

0.606

High

549855

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.580

High

1081325

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.580

High

1248604

LYPD5
Ly6/PLAUR domain-containing protein 5

2

0

High-throughput

0.580

High

1392000

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1392008

S19A3
Thiamine transporter 2

2

0

High-throughput

0.580

High

1392010

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.580

High

1392015

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.580

High

1392016

MARH2
E3 ubiquitin-protein ligase MARCHF2

2

0

High-throughput

0.580

High

1187531

AR13B
ADP-ribosylation factor-like protein 13B

2

3

High-throughput

0.553

High

1294808

STX12
Syntaxin-12

2

4

High-throughput

0.553

High

1327928

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

1

High-throughput

0.553

High

1359304

SSMM1
Serine-rich single-pass membrane protein 1

2

2

High-throughput

0.553

High

1384329

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.553

High

1062181

PCDH1
Protocadherin-1

1

2

High-throughput

0.536

High

1392023

JAG2
Protein jagged-2

1

1

High-throughput

0.536

High

338263

CLD9
Claudin-9

1

1

High-throughput

0.515

High

1387050

COQ8B
Atypical kinase COQ8B, mitochondrial

1

0

High-throughput

0.513

High

1392019

SUSD2
Sushi domain-containing protein 2

1

0

High-throughput

0.513

High

1228398

SE1L3
Protein sel-1 homolog 3

1

1

High-throughput

0.489

High

1287409

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.489

High

1391904

RN185
E3 ubiquitin-protein ligase RNF185

1

1

High-throughput

0.489

High

1392018

SE1L1
Protein sel-1 homolog 1

1

1

High-throughput

0.489

High

1392012

PCDH9
Protocadherin-9

1

2

High-throughput

0.479

High

814841

CUX1
Homeobox protein cut-like 1

1

1

High-throughput

0.437

High

1119453

CASP
Protein CASP

1

1

High-throughput

0.407

High

1312846

CI040
Uncharacterized protein C9orf40

3

0

High-throughput

0.347

High

1322486

TTC5
Tetratricopeptide repeat protein 5

3

0

High-throughput

0.347

High

1336205

RN214
RING finger protein 214

3

0

High-throughput

0.347

High

1392003

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

3

0

High-throughput

0.347

High

1392004

DCC1
Sister chromatid cohesion protein DCC1

3

0

High-throughput

0.347

High

1392011

ZN703
Zinc finger protein 703

3

0

High-throughput

0.347

High

319110

SC24D
Protein transport protein Sec24D

2

0

High-throughput

0.318

High

1392005

TMED9
Transmembrane emp24 domain-containing protein 9

2

0

High-throughput

0.316

High

1392009

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

0

High-throughput

0.316

High

1392024

UB2J1
Ubiquitin-conjugating enzyme E2 J1

2

0

High-throughput

0.316

High

1060204

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.279

Low

1105541

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

1197266

MBRL
Membralin

1

0

High-throughput

0.279

Low

1211186

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.279

Low

1218162

CAHD1
VWFA and cache domain-containing protein 1

1

0

High-throughput

0.279

Low

1245608

TXD11
Thioredoxin domain-containing protein 11

1

0

High-throughput

0.279

Low

1323826

INT1
Integrator complex subunit 1

1

0

High-throughput

0.279

Low

1363819

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.279

Low

1384176

TM186
Transmembrane protein 186

1

0

High-throughput

0.279

Low

1391998

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1392001

PRPK
EKC/KEOPS complex subunit TP53RK

1

0

High-throughput

0.279

Low

1392006

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.279

Low

1392013

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.279

Low

1392014

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.279

Low

1392017

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

1392022

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.279

Low

1338035

TMIE
Transmembrane inner ear expressed protein

1

0

High-throughput

0.251

Low

655886

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.249

Low

1242441

WDR73
Integrator complex assembly factor WDR73

1

0

High-throughput

0.249

Low

1334215

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.249

Low

1392002

UQCC2
Ubiquinol-cytochrome c reductase complex assembly factor 2

1

0

High-throughput

0.249

Low

1392021

APC10
Anaphase-promoting complex subunit 10

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025