Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: EPGN (Q6UW88)
Epigen (Epithelial mitogen) (EPG)
Gene: EPGN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 0.60 0.554

The method score is based on:

Property Details
Experiments 28988771
Identification Methods x ray scattering, x-ray crystallography, isothermal titration calorimetry
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0008284 - positive regulation of cell population proliferation
GO:0030297 - transmembrane receptor protein tyrosine kinase activator activity
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 154
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Last updated: 15 Jul 2024