Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: EPGN (Q6UW88)
Epigen (Epithelial mitogen) (EPG)
Gene: EPGN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.51 | 0.60 | 0.554 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28988771 |
Identification Methods | x ray scattering, x-ray crystallography, isothermal titration calorimetry |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0007173 - epidermal growth factor receptor signaling pathway GO:0008284 - positive regulation of cell population proliferation GO:0030297 - transmembrane receptor protein tyrosine kinase activator activity and 3 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024