HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: DJC11 (Q9NVH1)
DnaJ homolog subfamily C member 11
Gene: DNAJC11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	24797263
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 559
+	Hs
		338830 EGFR_HUMAN (1-1210): 0: 1241: 100.00		DNJA3_HUMAN (2-345): 9.19e-79: 257: 17.53
+	Hs
		338003 EGFR_HUMAN (1-1210): 0: 1241: 100.00		DNJA1_HUMAN (10-386): 1.49e-65: 220: 16.41
+	Hs
		243241 EGFR_HUMAN (1-1210): 0: 1241: 100.00		DNJA2_HUMAN (10-387): 6.01e-62: 211: 17.56
+	Hs
		339080 EGFR_HUMAN (1-1210): 0: 1241: 100.00		DJB11_HUMAN (1-196): 6.26e-38: 145: 22.89
+	Hs
		383929 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJA3_HUMAN (2-345): 9.19e-79: 257: 17.53
+	Hs
		383639 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJA1_HUMAN (10-386): 1.49e-65: 220: 16.41
+	Hs
		243250 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJA2_HUMAN (10-387): 6.01e-62: 211: 17.56
+	Hs
		601821 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		DNJA1_HUMAN (10-386): 1.49e-65: 220: 16.41
+	Hs
		384016 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DJB11_HUMAN (1-196): 6.26e-38: 145: 22.89
+	Hs
		257881 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJB6_HUMAN (14-109): 7.14e-38: 144: 44.76
+	Hs
		383889 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJB8_HUMAN (14-109): 3.7e-38: 142: 38.10
+	Hs
		602017 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		DJB11_HUMAN (1-196): 6.26e-38: 145: 22.89
+	Hs
		383619 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJB2_HUMAN (15-90): 2.59e-13: 73.2: 50.00
+	Hs
		243261 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		DNJA2_HUMAN (10-387): 6.01e-62: 211: 17.56
+	Hs
		411469 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		DNJA3_HUMAN (2-345): 9.19e-79: 257: 17.53
+	Hs
		411313 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		DNJA1_HUMAN (10-386): 1.49e-65: 220: 16.41
+	Hs
		243254 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		DNJA2_HUMAN (10-387): 6.01e-62: 211: 17.56
+	Hs
		434302 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		DJB11_HUMAN (1-196): 6.26e-38: 145: 22.89
+	Hs
		411515 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		DJB11_HUMAN (1-196): 6.26e-38: 145: 22.89
+	Hs
		537779 INSRR_HUMAN (352-656): 3.99e-25: 115: 20.90		DJB11_HUMAN (1-196): 6.26e-38: 145: 22.89