Protein: SWC4
SWR1-complex protein 4 (ESA1-associated factor 2)

Gene: SWC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P53201

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000812 - Swr1 complex
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

860102

SWR1
Helicase SWR1

19

7

Small-scale

0.764

High

797180

EPL1
Enhancer of polycomb-like protein 1

14

7

Small-scale

0.760

High

860110

ESA1
Histone acetyltransferase ESA1

13

7

Small-scale

0.757

High

755368

YNG2
Chromatin modification-related protein YNG2

7

5

Small-scale

0.749

High

860088

AF9
Protein AF-9 homolog

7

8

Small-scale

0.745

High

860098

RUVB1
RuvB-like protein 1

7

9

Small-scale

0.745

High

860116

H2AZ
Histone H2A.Z

7

3

Small-scale

0.742

High

860094

ARP4
Actin-related protein 4

6

11

Small-scale

0.732

High

860103

EAF1
Chromatin modification-related protein EAF1

9

0

Small-scale

0.720

High

860114

RUVB2
RuvB-like protein 2

5

9

Small-scale

0.716

High

860095

VPS72
Vacuolar protein sorting-associated protein 72

5

3

Small-scale

0.709

High

860113

EAF3
Chromatin modification-related protein EAF3

5

4

Small-scale

0.703

High

755436

TRA1
Transcription-associated protein 1

4

4

Small-scale

0.699

High

766422

EAF5
Chromatin modification-related protein EAF5

5

0

Small-scale

0.690

High

748512

SWC5
SWR1-complex protein 5

5

0

Small-scale

0.684

High

812211

EAF6
Chromatin modification-related protein EAF6

5

0

Small-scale

0.684

High

860087

EAF7
Chromatin modification-related protein EAF7

5

0

Small-scale

0.684

High

728726

BDF1
Bromodomain-containing factor 1

4

3

Small-scale

0.676

High

679795

SWC3
SWR1-complex protein 3

4

0

Small-scale

0.661

High

860107

SWC7
SWR1-complex protein 7

4

0

Small-scale

0.658

High

860092

ACT
Actin

3

6

Small-scale

0.650

High

860096

VPS71
Vacuolar protein sorting-associated protein 71

3

0

Small-scale

0.638

High

392163

H2A1
Histone H2A.1

2

1

Small-scale

0.584

High

860093

H3
Histone H3

2

3

High-throughput

0.571

High

860104

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.551

High

707036

MSN4
Zinc finger protein MSN4

2

0

High-throughput

0.547

High

676230

XPO1
Exportin-1

1

1

High-throughput

0.536

High

860105

PIN3
[PSI+] inducibility protein 3

1

0

High-throughput

0.518

High

436839

SWI5
Transcriptional factor SWI5

1

0

High-throughput

0.513

High

860086

SWC4
SWR1-complex protein 4

1

1

Small-scale

0.479

High

860090

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

860115

ARP6
Actin-like protein ARP6

1

10

High-throughput

0.479

High

566205

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

606706

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

619496

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.458

High

662846

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

716297

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

716475

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

860091

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

860099

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

860106

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

860109

SGO1
Shugoshin

1

0

High-throughput

0.458

High

860111

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

355562

H2B1
Histone H2B.1

1

4

High-throughput

0.445

High

356612

H4
Histone H4

1

1

High-throughput

0.445

High

491916

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494523

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

512106

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

633416

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

695160

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

769008

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

706040

NIP80
Protein NIP100

1

0

High-throughput

0.438

High

860089

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.438

High

515199

SCH9
Serine/threonine-protein kinase SCH9

1

0

High-throughput

0.426

High

612252

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

754571

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

809510

GUF1
Translation factor GUF1, mitochondrial

1

0

High-throughput

0.426

High

700999

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

792511

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

860100

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

693631

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.238

Low

860112

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.238

Low

446197

MYO1
Myosin-1

1

0

High-throughput

0.232

Low

705457

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

854926

NU188
Nucleoporin NUP188

1

0

High-throughput

0.232

Low

860097

TR130
Trafficking protein particle complex II-specific subunit 130

1

0

High-throughput

0.232

Low

860101

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

860108

YO075
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024