Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.710

The method score is based on:

Property Details
Experiments 25754235, 35384245, 20029029, 23956138, unassigned2173
Identification Methods affinity chromatography technology, proximity labelling technology, protein complementation assay, ubiquitin reconstruction, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0031965 - nuclear membrane
GO:0045296 - cadherin binding
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 249
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024