Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: RABX5 (Q9UJ41)
Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5)
Gene: RABGEF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.621

The method score is based on:

Property Details
Experiments 28065597, 16499958
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0031901 - early endosome membrane
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 491
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Mm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024