HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: GGA1 (Q9UJY5)
ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	29358589
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane GO:0016020 - membrane GO:0031901 - early endosome membrane GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 639
+	Hs
		339057 EGFR_HUMAN (1-1210): 0: 1241: 100.00		GGA3_HUMAN (6-639): 3.76e-158: 473: 48.47
+	Hs
		339109 EGFR_HUMAN (1-1210): 0: 1241: 100.00		GGA2_HUMAN (3-637): 9.87e-155: 461: 46.78
+	Hs
		212580 EGFR_HUMAN (1-1210): 0: 1241: 100.00		AP1G1_HUMAN (28-636): 1.9e-94: 310: 17.54
+	Hs
		276982 EGFR_HUMAN (1-1210): 0: 1241: 100.00		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		159830 EGFR_HUMAN (1-1210): 0: 1241: 100.00		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		272785 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TM1L1_HUMAN (7-461): 2.07e-74: 248: 19.23
+	Hs
		159886 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		434297 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		GGA3_HUMAN (6-639): 3.76e-158: 473: 48.47
+	Hs
		276988 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		159848 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		277037 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		277152 EPHA6_HUMAN (629-1016): 8.37e-118: 393: 27.80		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		277067 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		277010 EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79		STAM2_HUMAN (3-519): 1.16e-92: 297: 14.83
+	Hs
		159938 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		159900 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		665303 EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79		STAM1_HUMAN (3-519): 4.73e-90: 291: 16.05
+	Hs
		160216 EPHA6_HUMAN (629-1016): 8.37e-118: 393: 27.80		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		160004 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40
+	Hs
		159897 EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79		HGS_HUMAN (5-478): 9.91e-85: 283: 17.40