Protein: INP5K
Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase) (EC 3.1.3.86) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (Skeletal muscle and kidney-enriched inositol phosphatase)

Gene: INP5K, INPP5K
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q9BT40

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001726 - ruffle
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005000 - vasopressin receptor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1413105

NECT3
Nectin-3

3

1

High-throughput

0.861

High

1136756

MD2BP
MAD2L1-binding protein

7

0

High-throughput

0.717

High

1146129

K1H1
Keratin, type I cuticular Ha1

4

12

High-throughput

0.704

High

1139257

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

4

0

High-throughput

0.671

High

1379873

FATE1
Fetal and adult testis-expressed transcript protein

4

0

High-throughput

0.668

High

644546

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

4

0

High-throughput

0.667

High

1395757

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

3

2

High-throughput

0.662

High

1116775

AAMP
Angio-associated migratory cell protein

3

0

High-throughput

0.638

High

282483

KTNA1
Katanin p60 ATPase-containing subunit A1

2

2

High-throughput

0.628

High

507351

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

3

High-throughput

0.628

High

1413110

TR10D
Tumor necrosis factor receptor superfamily member 10D

2

2

High-throughput

0.606

High

1413113

GOT1B
Vesicle transport protein GOT1B

2

1

High-throughput

0.606

High

139594

PESC
Pescadillo homolog

2

0

High-throughput

0.602

High

1413107

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

2

0

High-throughput

0.602

High

339231

SFT2B
Vesicle transport protein SFT2B

2

0

High-throughput

0.580

High

1331892

FADS6
Fatty acid desaturase 6

2

0

High-throughput

0.580

High

1152788

PI5PA
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

1

3

High-throughput

0.575

High

651100

RFX1
MHC class II regulatory factor RFX1

2

1

High-throughput

0.574

High

1413108

ARL8B
ADP-ribosylation factor-like protein 8B

1

9

Small-scale

0.573

High

532913

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.536

High

871796

RFX3
Transcription factor RFX3

1

1

High-throughput

0.536

High

1122815

DOCK1
Dedicator of cytokinesis protein 1

1

2

High-throughput

0.536

High

1127674

KT33B
Keratin, type I cuticular Ha3-II

1

12

High-throughput

0.536

High

1129723

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.536

High

1413112

SNX6
Sorting nexin-6

1

5

High-throughput

0.536

High

415832

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

660295

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.518

High

1215028

CPTP
Ceramide-1-phosphate transfer protein

1

0

High-throughput

0.518

High

1369479

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.518

High

1383346

Q96AL5
PBX3 protein

1

1

High-throughput

0.515

High

567066

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.513

High

1243769

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.513

High

1310360

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1392874

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.513

High

1413101

GAN
Gigaxonin

1

0

High-throughput

0.513

High

628014

ANXA7
Annexin A7

1

2

High-throughput

0.508

High

1348465

LNX1
E3 ubiquitin-protein ligase LNX

1

3

Small-scale

0.506

High

332441

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

1

High-throughput

0.501

High

1413115

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

0

High-throughput

0.493

High

1369687

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

1413102

MTG2
Mitochondrial ribosome-associated GTPase 2

1

5

High-throughput

0.489

High

261866

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.486

High

405537

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

720029

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.486

High

808159

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

1160566

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

823979

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.481

High

1413116

NCOR2
Nuclear receptor corepressor 2

1

3

Small-scale

0.481

High

1413114

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

242754

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

945850

EPIPL
Epiplakin

1

2

High-throughput

0.479

High

1140774

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1413106

ANLN
Anillin

1

1

High-throughput

0.479

High

539632

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.458

High

693943

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

971001

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1010706

DCD
Dermcidin

1

0

High-throughput

0.458

High

1413103

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1413109

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

1413111

BRPF3
Bromodomain and PHD finger-containing protein 3

1

0

High-throughput

0.458

High

339105

NADK
NAD kinase

1

1

High-throughput

0.445

High

640275

EPHA1
Ephrin type-A receptor 1

1

5

High-throughput

0.445

High

942850

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

15

High-throughput

0.445

High

1413104

PAAT
ATPase PAAT

1

1

High-throughput

0.445

High

326008

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.426

High

564303

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

870300

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.426

High

1022560

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

0

High-throughput

0.426

High

1240946

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.426

High

1251793

S39A5
Zinc transporter ZIP5

1

0

High-throughput

0.426

High

1330605

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.426

High

1338629

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.426

High

1370625

GPKOW
G-patch domain and KOW motifs-containing protein

1

0

High-throughput

0.426

High

1387440

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.426

High

1390402

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.426

High

1397967

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.426

High

1412843

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.426

High

1413100

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.426

High

1413117

NPTN
Neuroplastin

1

0

High-throughput

0.426

High

1308955

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

1292669

PRSR2
Proline and serine-rich protein 2

2

0

High-throughput

0.328

High

617582

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

2

0

High-throughput

0.316

High

1336596

FSAF1
40S small subunit processome assembly factor 1

1

0

High-throughput

0.279

Low

389881

TTHY
Transthyretin

1

0

High-throughput

0.265

Low

1243230

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.249

Low

1312592

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1403679

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025