HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: HSP72 (P10592)
Heat shock protein SSA2
Gene: SSA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	24374311, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 298 Sc			1 639
+	Hs
		503460 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		HSP7C_HUMAN (2-639): 0: 948: 74.34
+	Hs
		713942 CDK3_HUMAN (5-295): 4.65e-147: 416: 63.92		HS71L_HUMAN (2-639): 0: 959: 72.08
+	Sc
		339379 CDK1_YEAST (1-298): 1.93e-142: 404: 100.00		HSP71_YEAST (1-639): 0: 969: 97.04
+	Hs
		503902 CDK3_HUMAN (5-295): 4.65e-147: 416: 63.92		HSP7C_HUMAN (2-639): 0: 948: 74.34
+	At
		612295 CDKA1_ARATH (5-297): 3.44e-139: 396: 61.22		HS701_ARATH (2-639): 0: 952: 71.16
+	Sc
		490253 PHO85_YEAST (6-297): 2.21e-126: 364: 52.67		HSP71_YEAST (1-639): 0: 969: 97.04
+	Sc
		493128 PHO85_YEAST (6-297): 2.21e-126: 364: 52.67		HSP72_YEAST (1-639): 0: 935: 100.00
+	Mm
		509463 CDK1_MOUSE (5-297): 2.56e-140: 399: 59.39		HSP72_MOUSE (4-607): 0: 870: 73.40