HitPredict

Interactor 1: KAD1 (P00568)
Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.10) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)
Gene: AK1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32812023, 35063084
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 194 Hs			1 758
+	Hs
		496641 KAD2_HUMAN (2-192): 3.95e-76: 229: 30.18		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		581941 KAD1_RAT (1-194): 2.6e-88: 259: 90.21		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94164 KAD1_RAT (1-194): 2.6e-88: 259: 90.21		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		340813 KAD1_HUMAN (1-194): 5.13e-88: 258: 100.00		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91