Protein: ZC3HE
Zinc finger CCCH domain-containing protein 14 (Mammalian suppressor of tau pathology-2) (MSUT-2) (Renal carcinoma antigen NY-REN-37)

Gene: ZC3HE, ZC3H14
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q6PJT7

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1245413

MKRN2
E3 ubiquitin-protein ligase makorin-2

2

1

High-throughput

0.789

High

472828

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

2

High-throughput

0.667

High

1245382

RALYL
RNA-binding Raly-like protein

3

4

High-throughput

0.667

High

1245395

SNIP1
Smad nuclear-interacting protein 1

3

1

High-throughput

0.667

High

1245440

LC7L2
Putative RNA-binding protein Luc7-like 2

3

1

High-throughput

0.667

High

372344

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.640

High

1226769

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

3

0

High-throughput

0.638

High

1245416

PININ
Pinin

3

0

High-throughput

0.634

High

1245431

WRP73
WD repeat-containing protein WRAP73

3

0

Small-scale

0.634

High

485662

RU2A
U2 small nuclear ribonucleoprotein A'

2

1

High-throughput

0.628

High

889591

CLK2
Dual specificity protein kinase CLK2

2

1

High-throughput

0.628

High

1090243

ELAV2
ELAV-like protein 2

2

2

High-throughput

0.628

High

1118066

DX39B
Spliceosome RNA helicase DDX39B

2

5

High-throughput

0.628

High

1245384

ZCH18
Zinc finger CCCH domain-containing protein 18

2

4

High-throughput

0.628

High

1245419

ZCC17
Zinc finger CCHC domain-containing protein 17

2

3

High-throughput

0.628

High

1245372

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

4

High-throughput

0.618

High

1245390

ZC3H8
Zinc finger CCCH domain-containing protein 8

1

2

High-throughput

0.618

High

1126955

RBM39
RNA-binding protein 39

2

3

High-throughput

0.611

High

907972

DYLT3
Dynein light chain Tctex-type 3

2

1

High-throughput

0.606

High

1013149

SARNP
SAP domain-containing ribonucleoprotein

2

0

High-throughput

0.602

High

1245391

CAMKV
CaM kinase-like vesicle-associated protein

2

0

High-throughput

0.602

High

1198576

NCBP3
Nuclear cap-binding protein subunit 3

3

0

High-throughput

0.597

High

134778

SAP18
Histone deacetylase complex subunit SAP18

2

0

High-throughput

0.585

High

1245428

WSB2
WD repeat and SOCS box-containing protein 2

2

1

High-throughput

0.574

High

396349

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

807471

IF4A3
Eukaryotic initiation factor 4A-III

2

3

High-throughput

0.571

High

1245406

THOC1
THO complex subunit 1

2

0

High-throughput

0.559

High

1245381

K1C27
Keratin, type I cytoskeletal 27

2

1

High-throughput

0.553

High

775436

DDIT3
DNA damage-inducible transcript 3 protein

1

0

High-throughput

0.549

High

777401

K1C20
Keratin, type I cytoskeletal 20

1

1

High-throughput

0.541

High

123126

DX39A
ATP-dependent RNA helicase DDX39A

1

5

High-throughput

0.536

High

256633

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

3

High-throughput

0.536

High

462475

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

5

High-throughput

0.536

High

466315

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.536

High

478091

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

High-throughput

0.536

High

481311

HMGB1
High mobility group protein B1

1

4

High-throughput

0.536

High

549180

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.536

High

574331

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

High-throughput

0.536

High

634493

LMNB1
Lamin-B1

1

2

High-throughput

0.536

High

854119

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

889757

CLK3
Dual specificity protein kinase CLK3

1

1

High-throughput

0.536

High

973953

RUXF
Small nuclear ribonucleoprotein F

1

3

High-throughput

0.536

High

1016481

SRSF3
Serine/arginine-rich splicing factor 3

1

4

High-throughput

0.536

High

1044354

HSF2
Heat shock factor protein 2

1

1

High-throughput

0.536

High

1051487

SRS11
Serine/arginine-rich splicing factor 11

1

3

High-throughput

0.536

High

1062018

SRSF4
Serine/arginine-rich splicing factor 4

1

3

High-throughput

0.536

High

1065249

SSRP1
FACT complex subunit SSRP1

1

3

High-throughput

0.536

High

1099398

SRSF6
Serine/arginine-rich splicing factor 6

1

5

High-throughput

0.536

High

1145238

RNPS1
RNA-binding protein with serine-rich domain 1

1

2

High-throughput

0.536

High

1149096

SF3A1
Splicing factor 3A subunit 1

1

1

High-throughput

0.536

High

1159973

SRSF7
Serine/arginine-rich splicing factor 7

1

3

High-throughput

0.536

High

1160174

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

2

High-throughput

0.536

High

1168826

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.536

High

1245401

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.536

High

1245403

PABP5
Polyadenylate-binding protein 5

1

1

High-throughput

0.536

High

1245405

RBM33
RNA-binding protein 33

1

1

High-throughput

0.536

High

1245422

DDX21
Nucleolar RNA helicase 2

1

4

High-throughput

0.536

High

1245425

ARGL1
Arginine and glutamate-rich protein 1

1

1

High-throughput

0.536

High

1245434

PUF60
Poly(U)-binding-splicing factor PUF60

1

4

High-throughput

0.536

High

1245435

RALY
RNA-binding protein Raly

1

3

High-throughput

0.536

High

1245439

TR150
Thyroid hormone receptor-associated protein 3

1

5

High-throughput

0.536

High

1245385

ARHGJ
Rho guanine nucleotide exchange factor 19

2

1

High-throughput

0.521

High

1027533

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.515

High

192599

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

272957

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

449652

CALCA
Calcitonin gene-related peptide 1

1

0

High-throughput

0.513

High

471091

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

480195

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

593670

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

841792

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.513

High

1025314

CDKL1
Cyclin-dependent kinase-like 1

1

0

High-throughput

0.513

High

1049438

1433F
14-3-3 protein eta

1

0

High-throughput

0.513

High

1117188

THOC5
THO complex subunit 5

1

0

High-throughput

0.513

High

1152112

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1178049

RN151
RING finger protein 151

1

0

High-throughput

0.513

High

1233192

THOC7
THO complex subunit 7

1

0

High-throughput

0.513

High

1234692

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.513

High

1245389

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.513

High

1245394

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.513

High

1245402

SH3K1
SH3 domain-containing kinase-binding protein 1

1

0

High-throughput

0.513

High

1245408

KAD7
Adenylate kinase 7

1

0

High-throughput

0.513

High

1245442

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.513

High

1245443

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.513

High

1245407

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

2

High-throughput

0.501

High

1137784

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.489

High

1245420

LUC7L
Putative RNA-binding protein Luc7-like 1

1

1

High-throughput

0.489

High

508154

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1245404

HOOK2
Protein Hook homolog 2

1

0

Small-scale

0.480

High

157516

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

260097

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

1245386

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1245387

SRRM1
Serine/arginine repetitive matrix protein 1

1

5

High-throughput

0.479

High

272270

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

345961

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

406298

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

542077

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.479

High

551110

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

588960

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

606861

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

695746

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

862234

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

886970

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.479

High

891209

GSK3A
Glycogen synthase kinase-3 alpha

1

2

High-throughput

0.479

High

979854

H4
Histone H4

1

2

High-throughput

0.479

High

991866

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.479

High

1026434

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

1083388

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.479

High

1096725

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

1128032

DHX8
ATP-dependent RNA helicase DHX8

1

2

High-throughput

0.479

High

1134241

IMB1
Importin subunit beta-1

1

3

High-throughput

0.479

High

1152531

ELAV1
ELAV-like protein 1

1

1

High-throughput

0.479

High

1161497

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1199314

GLE1
mRNA export factor GLE1

1

3

High-throughput

0.479

High

1235447

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1245377

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1245379

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1245383

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1245393

THOC2
THO complex subunit 2

1

3

High-throughput

0.479

High

1245397

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1245400

FUBP1
Far upstream element-binding protein 1

1

3

High-throughput

0.479

High

1245409

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.479

High

1245415

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1245417

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.479

High

1245418

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1245424

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

1245427

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1245430

HECW2
E3 ubiquitin-protein ligase HECW2

1

2

High-throughput

0.479

High

1245432

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

1245433

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1245441

3BP1
SH3 domain-binding protein 1

1

1

High-throughput

0.479

High

1245444

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.479

High

129193

MEN1
Menin

1

0

High-throughput

0.458

High

567427

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

974943

TYB4
Thymosin beta-4

1

0

High-throughput

0.458

High

1100841

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1113444

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1134955

CUL7
Cullin-7

1

0

High-throughput

0.458

High

1137352

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1155471

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1245373

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1245392

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1245396

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1245398

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1245399

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1245411

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

1245412

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1245426

AATF
Protein AATF

1

0

High-throughput

0.458

High

529976

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

880803

NRAM1
Natural resistance-associated macrophage protein 1

1

1

High-throughput

0.445

High

880842

NRAM2
Natural resistance-associated macrophage protein 2

1

1

High-throughput

0.445

High

1066687

NCBP1
Nuclear cap-binding protein subunit 1

1

1

High-throughput

0.445

High

1245410

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

3

High-throughput

0.445

High

1245414

PAR12
Protein mono-ADP-ribosyltransferase PARP12

1

2

High-throughput

0.445

High

1245445

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

3

High-throughput

0.445

High

768468

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1060713

SOS2
Son of sevenless homolog 2

1

1

High-throughput

0.437

High

1226900

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1245436

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.437

High

1245437

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

1015238

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.426

High

1220498

BTBD8
BTB/POZ domain-containing protein 8

1

0

High-throughput

0.426

High

861655

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

High-throughput

0.408

High

1245374

ZNT10
Calcium/manganese antiporter SLC30A10

1

3

High-throughput

0.407

High

1245388

S22AO
Steroid transmembrane transporter SLC22A24

1

1

High-throughput

0.407

High

1245378

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

1245438

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.282

High

657606

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.249

Low

1245376

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1245421

ANLN
Anillin

1

0

High-throughput

0.249

Low

1245423

ARHG4
Rho guanine nucleotide exchange factor 4

1

0

High-throughput

0.249

Low

1245429

RHG23
Rho GTPase-activating protein 23

1

0

High-throughput

0.249

Low

190401

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low

1245375

S39A5
Zinc transporter ZIP5

1

0

High-throughput

0.232

Low

1245380

S46A3
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025