HitPredict

Interactor 1: PLMN (P00747)
Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]
Gene: PLG

Interactor 2: SPRC (P09486)
SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine)
Gene: SPARC

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.812

The method score is based on:

Property	Details
Experiments	7982919, 7514608
Identification Methods	pull down, solid phase assay, protease assay
Interaction Type	direct interaction, physical association, protein cleavage

The annotation score is based on:

Property	Details
Interacting Pfam domains	Kazal_1~Trypsin
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0031093 - platelet alpha granule lumen and 1 others more... GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	810
Hs

1	303

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024