HitPredict

Interactor 1: CFAB (P00751)
Complement factor B (EC 3.4.21.47) (C3/C5 convertase) (Glycine-rich beta glycoprotein) (GBG) (PBF2) (Properdin factor B) [Cleaved into: Complement factor B Ba fragment; Complement factor B Bb fragment]
Gene: CFB

Interactor 2: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 764 Hs			1 450
+	Hs
		341587 CFAB_HUMAN (1-764): 0: 574: 100.00		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		1037390 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		589992 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		341414 FA12_HUMAN (131-756): 3.56e-70: 243: 13.80		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		1114233 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		428427 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		341411 FA12_HUMAN (131-756): 3.56e-70: 243: 13.80		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		933971 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		589994 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB8_HUMAN (1-427): 0: 705: 87.59
+	Hs
		1046575 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB2A_HUMAN (1-430): 0: 700: 93.49
+	Hs
		1312808 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB6_HUMAN (1-446): 0: 700: 92.38
+	Hs
		428014 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB5_HUMAN (1-429): 0: 704: 93.94
+	Hs
		381298 TMPS5_HUMAN (321-761): 3.69e-70: 239: 16.22		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		589991 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB4B_HUMAN (1-427): 0: 703: 93.91
+	Hs
		589997 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB2B_HUMAN (1-430): 0: 703: 93.72
+	Hs
		381216 PRSS8_HUMAN (471-756): 1.88e-70: 236: 21.09		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		589993 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB2A_HUMAN (1-430): 0: 700: 93.49
+	Hs
		381121 TRYB2_HUMAN (471-753): 7.11e-71: 235: 19.38		TBB4A_HUMAN (1-427): 0: 699: 93.21
+	Hs
		1037431 TSP50_HUMAN (490-761): 6.66e-54: 192: 21.58		TBB3_HUMAN (1-450): 0: 723: 100.00
+	Hs
		428487 TSP50_HUMAN (490-761): 6.66e-54: 192: 21.58		TBB5_HUMAN (1-429): 0: 704: 93.94