HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: JUND (P17535)
Transcription factor JunD (Transcription factor AP-1 subunit JunD)
Gene: JUND

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 26186194, 26496610, 25609649, 28514442, 33961781, 35140242, 11431474, 20195357, 20102225, 24029232
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, peptide array, tandem affinity purification, anti tag coimmunoprecipitation, display technology, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_1
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001221 - transcription coregulator binding
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024