HitPredict

Interactor 1: FOS (P01101)
Protein c-Fos (Cellular oncogene fos) (FBJ osteosarcoma oncogene) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: ATF7 (Q8R0S1)
Cyclic AMP-dependent transcription factor ATF-7 (cAMP-dependent transcription factor ATF-7) (Activating transcription factor 7) (Transcription factor ATF-A)
Gene: ATF7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15867431
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_1
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 380 Mm			1 413
+	Hs
		345313 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		ATF7_HUMAN (1-411): 5.69e-103: 315: 97.32
+	Hs
		345305 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		ATF2_HUMAN (1-407): 1.37e-80: 258: 57.11
+	Hs
		547818 Q6FG41_HUMAN (1-380): 5.98e-81: 254: 93.68		ATF2_HUMAN (1-407): 1.37e-80: 258: 57.11
+	Hs
		345402 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		CREB5_HUMAN (1-411): 3.4e-63: 213: 36.04
+	Hs
		973584 Q6FG41_HUMAN (1-380): 5.98e-81: 254: 93.68		CREB5_HUMAN (1-411): 3.4e-63: 213: 36.04
+	Mm
		345599 FOS_MOUSE (1-380): 1.95e-83: 260: 100.00		JUNB_MOUSE (77-404): 1.24e-44: 159: 16.47
+	Mm
		345596 FOS_MOUSE (1-380): 1.95e-83: 260: 100.00		JUN_MOUSE (77-408): 2.01e-43: 156: 17.11
+	Hs
		345280 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		JUN_HUMAN (77-408): 5.68e-45: 160: 17.56
+	Rn
		522309 FOS_RAT (1-380): 5.82e-82: 256: 96.84		JUN_RAT (77-408): 4.68e-43: 155: 16.81
+	Hs
		345311 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		JUNB_HUMAN (77-404): 6.71e-39: 144: 16.33
+	Hs
		566766 Q6FG41_HUMAN (1-380): 5.98e-81: 254: 93.68		JUNB_HUMAN (77-404): 6.71e-39: 144: 16.33
+	Mm
		345602 FOS_MOUSE (1-380): 1.95e-83: 260: 100.00		JUND_MOUSE (92-407): 3.94e-32: 126: 17.67
+	Hs
		345403 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		CREM_HUMAN (80-383): 9.1e-32: 125: 15.36
+	Hs
		345309 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		CREB1_HUMAN (78-387): 1.05e-31: 124: 13.58
+	Hs
		345312 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		JUND_HUMAN (94-407): 3.4e-29: 118: 17.61
+	Mm
		345615 FOS_MOUSE (1-380): 1.95e-83: 260: 100.00		ATF4_MOUSE (190-394): 1.03e-25: 108: 18.22
+	Hs
		345319 FOS_HUMAN (1-380): 5.98e-81: 254: 93.68		ATF4_HUMAN (192-394): 1.89e-26: 110: 16.96
+	Hs
		1147395 CR3L3_HUMAN (4-342): 5.75e-50: 176: 15.60		CR3L3_HUMAN (130-408): 4.92e-34: 133: 17.73
+	Hs
		556890 CR3L3_HUMAN (4-342): 5.75e-50: 176: 15.60		CREB1_HUMAN (78-387): 1.05e-31: 124: 13.58
+	Hs
		579347 CR3L3_HUMAN (4-342): 5.75e-50: 176: 15.60		ATF6A_HUMAN (180-387): 4.02e-25: 109: 19.23