HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: TRFE (P02787)
Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Siderophilin)
Gene: TF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35013218, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006879 - intracellular iron ion homeostasis GO:0045893 - positive regulation of DNA-templated transcription GO:0070371 - ERK1 and ERK2 cascade
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 698
+	Hs
		345643 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TRFL_HUMAN (1-697): 0: 977: 60.22