HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	35013218, 36424410, 20195357
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, display technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 437
+	Hs
		345797 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		347423 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17
+	Hs
		348353 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73
+	Hs
		346697 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		346545 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18
+	Hs
		346042 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIA1_HUMAN (98-338): 2.21e-18: 88.4: 12.95
+	Hs
		235649 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55
+	Hs
		347794 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBM24_HUMAN (98-177): 1.49e-15: 77.5: 31.25
+	Hs
		378957 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08
+	Hs
		378926 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		380071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73
+	Hs
		379365 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81
+	Hs
		379302 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18
+	Hs
		379055 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIA1_HUMAN (98-338): 2.21e-18: 88.4: 12.95
+	Hs
		235657 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55
+	Hs
		379815 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RBM24_HUMAN (98-177): 1.49e-15: 77.5: 31.25
+	Dm
		1129090 Q9W4Q7_DROME (358-449): 5.64e-19: 91.7: 29.03		SET1_DROME (53-387): 1.25e-41: 160: 20.59