HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 372
+	Hs
		347563 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87
+	Hs
		346935 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44
+	Hs
		161927 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		345935 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		346283 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		347702 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		346655 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		346751 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		346697 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		346042 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71
+	Hs
		378940 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		379462 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44
+	Hs
		161930 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		379017 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		379149 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		379345 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		379389 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		379700 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MSI2H_HUMAN (2-91): 6.69e-16: 79.8: 35.56
+	Hs
		379365 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		379055 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71