HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PDLI4 (P50479)
PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein)
Gene: PDLIM4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	35013218, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 330
+	Hs
		117239 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PDLI1_HUMAN (2-324): 6.41e-52: 176: 42.25
+	Hs
		348227 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SYNP2_HUMAN (5-245): 1.47e-31: 126: 22.82
+	Hs
		346707 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNTB2_HUMAN (5-277): 3.75e-30: 121: 15.83
+	Hs
		346876 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TRIP6_HUMAN (19-328): 1.69e-26: 110: 12.39
+	Hs
		347012 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGI3_HUMAN (7-169): 5.12e-13: 72.1: 18.90
+	Hs
		347647 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGI1_HUMAN (6-216): 3.73e-11: 66.3: 14.55
+	Hs
		347985 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PDLI7_HUMAN (216-305): 1.44e-09: 60.9: 17.20
+	Hs
		380016 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SYNP2_HUMAN (5-245): 1.47e-31: 126: 22.82