HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.715

Property	Details
Experiments	30415952, 35013218, 36424410, 17314511, 21988832
Identification Methods	proximity labelling technology, affinity chromatography technology, two hybrid, tandem affinity purification, two hybrid array
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 529
+	Hs
		134819 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38
+	Hs
		131358 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06
+	Hs
		168608 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02
+	Hs
		346287 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Hs
		379151 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00
+	Hs
		131364 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06
+	Hs
		168610 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02