HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26496610, 29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1226
+	Hs
		379169 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DSRAD_HUMAN (1-1226): 0: 1785: 100.00
+	Hs
		345898 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45
+	Hs
		347454 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DGCR8_HUMAN (474-762): 2.83e-47: 184: 17.94
+	Hs
		269596 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89
+	Hs
		346871 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TRBP2_HUMAN (589-807): 3.88e-36: 143: 21.81
+	Hs
		347663 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83
+	Hs
		348014 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		STAU2_HUMAN (470-829): 3.1e-28: 123: 17.54
+	Hs
		346654 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		322048 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		379006 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		E2AK2_HUMAN (505-857): 1.48e-55: 205: 18.45
+	Hs
		379662 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DGCR8_HUMAN (474-762): 2.83e-47: 184: 17.94
+	Hs
		269599 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89
+	Hs
		379442 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TRBP2_HUMAN (589-807): 3.88e-36: 143: 21.81
+	Hs
		379759 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83
+	Hs
		379923 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		STAU2_HUMAN (470-829): 3.1e-28: 123: 17.54
+	Hs
		379344 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		322057 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		379272 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05
+	Hs
		322849 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95