HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

Property	Details
Experiments	29467282, 35013218, 36424410, 21988832
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 199
+	Hs
		346054 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		346023 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		346680 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		346021 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50
+	Hs
		379319 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRDX1_HUMAN (1-199): 2.21e-105: 302: 100.00
+	Hs
		379061 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		379048 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		379355 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		379047 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50