HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 261
+	Hs
		346659 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO1E_HUMAN (36-261): 8.28e-25: 105: 15.04
+	Hs
		348184 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DBNL_HUMAN (59-261): 2.02e-25: 105: 23.65
+	Hs
		347715 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SH3G1_HUMAN (48-261): 6.99e-24: 100: 18.81
+	Hs
		346771 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRC8_HUMAN (38-260): 4.28e-23: 99: 17.62
+	Hs
		345853 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PLCG2_HUMAN (15-261): 2.82e-22: 98: 13.77
+	Hs
		347805 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PACN1_HUMAN (6-261): 2.88e-22: 96.9: 19.09
+	Hs
		100125 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		F6U236_HUMAN (6-261): 4.21e-22: 96.1: 19.09
+	Hs
		346301 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CRIP2_HUMAN (1-54): 1.16e-17: 80.7: 42.59
+	Hs
		347795 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRBS1_HUMAN (149-259): 7.54e-13: 69.9: 31.30
+	Hs
		380028 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		379134 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CRIP1_HUMAN (3-54): 2.22e-22: 89.5: 46.15
+	Hs
		379158 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CRIP2_HUMAN (1-54): 1.16e-17: 80.7: 42.59