HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CTR9 (Q6PD62)
RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1)
Gene: CTR9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	26687678, 29467282, 36424410, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1173
+	Dm
		1178774 MYC_DROME (210-454): 3.25e-30: 126: 26.74		Q7K0X3_DROME (6-1016): 2.45e-126: 418: 62.15
+	Hs
		174528 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		OGT1_HUMAN (10-501): 1.15e-43: 175: 13.19
+	Hs
		300023 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02
+	Mm
		1208456 MLXPL_MOUSE (70-447): 2.06e-31: 129: 14.14		OGT1_MOUSE (10-501): 1.06e-43: 175: 13.19
+	Hs
		379516 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SKI3_HUMAN (9-514): 3.93e-11: 69.9: 9.36
+	Hs
		300027 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRP6_HUMAN (32-285): 7.01e-11: 68.7: 12.02