HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SRPK1 (Q96SB4)
SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
Gene: SRPK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 655
+	Hs
		379758 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SRPK1_HUMAN (1-655): 5.68e-157: 468: 94.64
+	Hs
		379269 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SRPK2_HUMAN (48-655): 9.43e-136: 415: 57.97
+	Hs
		585126 TFEB_HUMAN (180-450): 2.56e-28: 118: 14.59		SRPK1_HUMAN (1-655): 5.68e-157: 468: 94.64
+	Hs
		346238 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CLK3_HUMAN (484-653): 1.02e-60: 216: 28.65
+	Hs
		347148 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MARK2_HUMAN (409-654): 1.03e-46: 178: 12.70
+	Hs
		983430 MAD1_HUMAN (320-453): 2.08e-29: 116: 19.40		KS6A1_HUMAN (1-359): 2.84e-81: 273: 14.32
+	Hs
		379041 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MARK3_HUMAN (409-655): 3.06e-47: 179: 12.65
+	Hs
		379539 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MARK2_HUMAN (409-654): 1.03e-46: 178: 12.70
+	Hs
		252931 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		CLK4_HUMAN (436-654): 5.51e-63: 218: 23.89
+	At
		1105320 MYC2_ARATH (200-454): 1.78e-32: 132: 18.05		KIN10_ARATH (414-655): 1.35e-54: 196: 15.32
+	Hs
		252905 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		MARK3_HUMAN (409-655): 3.06e-47: 179: 12.65