HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21150319
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0071456 - cellular response to hypoxia
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 447
+	Hs
		346638 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TBL3_HUMAN (12-447): 1.29e-58: 207: 13.88
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (3-218): 5.36e-51: 179: 11.86
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		267729 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TAF5L_HUMAN (76-247): 1.76e-26: 114: 15.76
+	Hs
		346472 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (356-445): 8.01e-19: 90.6: 15.56
+	Hs
		282800 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CIAO1_HUMAN (81-215): 3.8e-16: 81.1: 18.12
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		379258 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		267736 MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11		TAF5L_HUMAN (76-247): 1.76e-26: 114: 15.76
+	Hs
		1218698 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Mm
		659344 MAX_MOUSE (354-454): 3.52e-25: 102: 32.67		WDR5_MOUSE (4-165): 6.22e-31: 123: 8.93
+	Hs
		898091 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		267750 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		TAF5L_HUMAN (76-247): 1.76e-26: 114: 15.76
+	At
		189017 MYC2_ARATH (200-454): 1.78e-32: 132: 18.05		GBLPA_ARATH (76-217): 7.82e-12: 68: 15.79