HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	29467282, 35013218, 17314511, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010468 - regulation of gene expression
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 599
+	Hs
		127974 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		348086 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		380081 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		127979 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		379960 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		346354 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP3_HUMAN (385-597): 7.22e-39: 148: 24.31
+	Hs
		346847 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		347594 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		346405 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Mm
		348413 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		HNRPK_MOUSE (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		346533 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Hs
		347503 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP2_HUMAN (414-584): 1.07e-10: 66.6: 28.73
+	Hs
		346846 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69
+	Hs
		379180 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP3_HUMAN (385-597): 7.22e-39: 148: 24.31
+	Hs
		379429 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		379728 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		379201 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		379683 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP2_HUMAN (414-584): 1.07e-10: 66.6: 28.73
+	Hs
		379428 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69