HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1130
+	Hs
		349879 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613251 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		349128 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613237 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613233 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		349134 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		349814 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443078 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		349097 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		348477 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		349073 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		530549 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		443061 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		530555 RAP1B_HUMAN (1-165): 1.02e-61: 191: 56.89		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Mm
		919010 RAB1A_MOUSE (4-187): 1.35e-76: 229: 33.33		ITA2B_MOUSE (10-1088): 0: 801: 22.31
+	Hs
		349856 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566881 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		349109 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566871 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566866 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22