HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: MOT1 (P53985)
Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1)
Gene: SLC16A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	30442766, 30194290, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 500
+	Hs
		350001 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00
+	Hs
		866947 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00
+	Hs
		349219 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00
+	Hs
		866925 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00
+	Hs
		866918 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00
+	Hs
		894772 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		MOT11_HUMAN (2-441): 3.12e-71: 235: 26.74
+	Hs
		506372 RALA_HUMAN (4-169): 7.15e-59: 184: 53.89		MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00
+	Hs
		918909 RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33		MOT11_HUMAN (2-441): 3.12e-71: 235: 26.74
+	Hs
		1241612 RAB1B_HUMAN (4-187): 1.35e-75: 226: 33.51		MOT11_HUMAN (2-441): 3.12e-71: 235: 26.74
+	Hs
		1079945 RB11B_HUMAN (4-184): 2.97e-73: 221: 32.79		MOT11_HUMAN (2-441): 3.12e-71: 235: 26.74
+	Hs
		179077 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49
+	Hs
		327727 RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33		MOT3_HUMAN (6-499): 3.66e-62: 212: 37.85
+	Hs
		179093 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49