HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: XCT (Q9UPY5)
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
Gene: SLC7A11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 501
+	Hs
		350407 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		YLAT2_HUMAN (3-501): 5.33e-122: 368: 43.71
+	Hs
		350692 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		349736 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		XCT_HUMAN (1-501): 1.35e-118: 359: 100.00
+	Hs
		350085 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		966066 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		348622 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		349255 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		LAT1_HUMAN (23-498): 1.09e-104: 323: 47.28
+	Hs
		350004 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		873920 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		348593 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		349223 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		349996 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		854884 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		349913 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		676544 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		873901 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		S12A2_HUMAN (12-485): 3.69e-84: 284: 14.15
+	Hs
		348588 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86
+	Hs
		348533 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		349149 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		CTR1_HUMAN (34-414): 2.9e-79: 261: 20.24
+	Hs
		854872 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		CTR2_HUMAN (36-414): 4.19e-80: 264: 19.86