HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: TRPV2 (Q9Y5S1)
Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)
Gene: TRPV2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30442766
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 764
+	Hs
		350728 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TRPV2_HUMAN (1-764): 0: 658: 100.00
+	Hs
		349759 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		TRPV2_HUMAN (1-764): 0: 658: 100.00
+	Mm
		1161503 RAB35_MOUSE (4-171): 6.96e-84: 247: 34.71		TRPV1_MOUSE (2-734): 0: 553: 45.01
+	Mm
		804668 RB11B_MOUSE (4-184): 2.28e-73: 221: 32.79		TRPV1_MOUSE (2-734): 0: 553: 45.01
+	Mm
		919693 RAP1A_MOUSE (1-165): 1.22e-60: 188: 56.29		TRPV1_MOUSE (2-734): 0: 553: 45.01
+	Mm
		930585 RALA_MOUSE (4-169): 1.3e-58: 184: 53.89		TRPV1_MOUSE (2-734): 0: 553: 45.01
+	Hs
		350464 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TRPM7_HUMAN (346-674): 6.07e-62: 228: 15.94
+	Hs
		1070351 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		TRPM7_HUMAN (346-674): 6.07e-62: 228: 15.94
+	Hs
		348875 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		TRPM7_HUMAN (346-674): 6.07e-62: 228: 15.94
+	Hs
		349579 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		TRPM7_HUMAN (346-674): 6.07e-62: 228: 15.94
+	Hs
		895234 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		TRPM7_HUMAN (346-674): 6.07e-62: 228: 15.94