Protein: STK38
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)

Gene: STK38
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q15208

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144332

M3K2
Mitogen-activated protein kinase kinase kinase 2

3

11

Small-scale

0.827

High

1144330

ST38L
Serine/threonine-protein kinase 38-like

2

16

High-throughput

0.811

High

857460

NOTC1
Neurogenic locus notch homolog protein 1

2

8

Small-scale

0.789

High

1098788

M3K1
Mitogen-activated protein kinase kinase kinase 1

2

19

Small-scale

0.754

High

1144280

MOB2
MOB kinase activator 2

7

20

Small-scale

0.746

High

363311

EGFR
Epidermal growth factor receptor

2

19

High-throughput

0.737

High

440081

LCK
Tyrosine-protein kinase Lck

2

18

High-throughput

0.737

High

631234

RAB5A
Ras-related protein Rab-5A

2

6

High-throughput

0.737

High

1038299

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

17

High-throughput

0.737

High

1144328

GAB2
GRB2-associated-binding protein 2

2

8

High-throughput

0.737

High

1144282

MOB1B
MOB kinase activator 1B

6

20

Small-scale

0.735

High

74497

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

4

High-throughput

0.691

High

136088

PLK4
Serine/threonine-protein kinase PLK4

1

14

High-throughput

0.691

High

1144306

DUS16
Dual specificity protein phosphatase 16

1

3

High-throughput

0.691

High

1144326

PRDM4
PR domain zinc finger protein 4

1

1

High-throughput

0.691

High

1144312

MOB1A
MOB kinase activator 1A

4

20

Small-scale

0.691

High

468394

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.665

High

374608

RASH
GTPase HRas

1

17

Small-scale

0.647

High

1144263

STK38
Serine/threonine-protein kinase 38

1

16

Small-scale

0.647

High

1144317

SMUF1
E3 ubiquitin-protein ligase SMURF1

3

18

Small-scale

0.640

High

1144288

MALD2
MARVEL domain-containing protein 2

2

3

High-throughput

0.628

High

841366

RBM34
RNA-binding protein 34

1

8

High-throughput

0.618

High

1144321

RBM28
RNA-binding protein 28

1

6

High-throughput

0.618

High

241739

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.618

High

247337

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

14

High-throughput

0.618

High

350010

SNAI1
Zinc finger protein SNAI1

1

5

High-throughput

0.618

High

425514

ISG15
Ubiquitin-like protein ISG15

1

4

Small-scale

0.618

High

461498

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

573831

CCNB1
G2/mitotic-specific cyclin-B1

1

6

Small-scale

0.618

High

762005

GRK5
G protein-coupled receptor kinase 5

1

15

High-throughput

0.618

High

822671

VHL
von Hippel-Lindau disease tumor suppressor

1

3

Small-scale

0.618

High

881528

CDK8
Cyclin-dependent kinase 8

1

12

Small-scale

0.618

High

897276

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.618

High

976280

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.618

High

1032982

EWS
RNA-binding protein EWS

1

8

High-throughput

0.618

High

1051238

KPCZ
Protein kinase C zeta type

1

17

High-throughput

0.618

High

1137039

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

3

High-throughput

0.618

High

1144268

LARP7
La-related protein 7

1

10

High-throughput

0.618

High

1144278

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.618

High

1144305

CDK19
Cyclin-dependent kinase 19

1

16

Small-scale

0.618

High

1144311

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

594006

NCK1
SH2/SH3 adapter protein NCK1

2

15

High-throughput

0.611

High

717307

PEBP1
Phosphatidylethanolamine-binding protein 1

2

2

High-throughput

0.611

High

957390

UBC12
NEDD8-conjugating enzyme Ubc12

2

4

High-throughput

0.611

High

1144300

CRBN
Protein cereblon

1

0

Small-scale

0.586

High

1144289

BANP
Protein BANP

2

0

High-throughput

0.580

High

1144337

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

1

Small-scale

0.578

High

354700

PAK4
Serine/threonine-protein kinase PAK 4

1

17

High-throughput

0.575

High

1144279

NEK10
Serine/threonine-protein kinase Nek10

1

14

High-throughput

0.575

High

1144297

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

5

Small-scale

0.575

High

1144301

ZBT18
Zinc finger and BTB domain-containing protein 18

1

2

High-throughput

0.575

High

791398

SYUA
Alpha-synuclein

2

3

High-throughput

0.571

High

855630

CRK
Adapter molecule crk

2

7

High-throughput

0.571

High

905747

CAV2
Caveolin-2

2

4

High-throughput

0.571

High

1144303

SH3G3
Endophilin-A3

2

9

High-throughput

0.571

High

407627

S100B
Protein S100-B

1

9

Small-scale

0.561

High

998340

H31
Histone H3.1

1

9

High-throughput

0.561

High

1094899

TRAF3
TNF receptor-associated factor 3

1

17

Small-scale

0.561

High

1144315

SENP2
Sentrin-specific protease 2

1

1

Small-scale

0.561

High

1041073

CAV1
Caveolin-1

2

4

High-throughput

0.558

High

318783

RHBT1
Rho-related BTB domain-containing protein 1

1

20

High-throughput

0.553

High

944997

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.553

High

1126895

RBM39
RNA-binding protein 39

1

6

High-throughput

0.553

High

1144307

RHBT2
Rho-related BTB domain-containing protein 2

1

20

High-throughput

0.553

High

1144322

FKB11
Peptidyl-prolyl cis-trans isomerase FKBP11

1

8

High-throughput

0.553

High

175053

SC16A
Protein transport protein Sec16A

1

4

High-throughput

0.536

High

219177

LTOR5
Ragulator complex protein LAMTOR5

1

1

High-throughput

0.536

High

483337

CLCB
Clathrin light chain B

1

1

High-throughput

0.536

High

529833

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.536

High

543507

VDR
Vitamin D3 receptor

1

15

High-throughput

0.536

High

732600

ARRB2
Beta-arrestin-2

1

8

High-throughput

0.536

High

839278

MTOR
Serine/threonine-protein kinase mTOR

1

14

Small-scale

0.536

High

861172

MAP1B
Microtubule-associated protein 1B

1

7

High-throughput

0.536

High

882494

ARRB1
Beta-arrestin-1

1

8

High-throughput

0.536

High

964619

DCAF7
DDB1- and CUL4-associated factor 7

1

7

High-throughput

0.536

High

1008165

PRKDC
DNA-dependent protein kinase catalytic subunit

1

12

High-throughput

0.536

High

1123909

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

High-throughput

0.536

High

1144270

UBR4
E3 ubiquitin-protein ligase UBR4

1

2

High-throughput

0.536

High

1144277

RICTR
Rapamycin-insensitive companion of mTOR

1

1

Small-scale

0.536

High

1144284

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

3

High-throughput

0.536

High

1144292

HDAC2
Histone deacetylase 2

1

10

High-throughput

0.536

High

1144304

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

4

Small-scale

0.536

High

1144314

LN28A
Protein lin-28 homolog A

1

4

High-throughput

0.536

High

1144316

MOV10
Helicase MOV-10

1

1

High-throughput

0.536

High

1144329

NCKP1
Nck-associated protein 1

1

1

High-throughput

0.536

High

1144334

EXOS1
Exosome complex component CSL4

1

1

High-throughput

0.536

High

729856

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.515

High

990252

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.515

High

1144272

MYSM1
Deubiquitinase MYSM1

1

4

Small-scale

0.515

High

1144336

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

4

Small-scale

0.515

High

568643

GYS1
Glycogen [starch] synthase, muscle

1

0

High-throughput

0.513

High

621880

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

1118282

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.513

High

1144313

AGO3
Protein argonaute-3

1

0

High-throughput

0.513

High

1125108

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

7

Small-scale

0.501

High

1144265

H2A2C
Histone H2A type 2-C

1

5

High-throughput

0.501

High

1144266

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.501

High

1144324

HERC5
E3 ISG15--protein ligase HERC5

1

20

Small-scale

0.501

High

1144267

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.489

High

1121219

TRI14
Tripartite motif-containing protein 14

1

8

High-throughput

0.481

High

138119

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

155111

SOCS2
Suppressor of cytokine signaling 2

1

20

Small-scale

0.479

High

257463

PAGE4
P antigen family member 4

1

1

High-throughput

0.479

High

259980

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.479

High

293717

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

319781

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

396152

ESR1
Estrogen receptor

1

19

High-throughput

0.479

High

413875

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

447045

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

547615

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

Small-scale

0.479

High

555396

SKI
Ski oncogene

1

4

Small-scale

0.479

High

556093

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

588752

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

603986

CXA1
Gap junction alpha-1 protein

1

6

Small-scale

0.479

High

684248

DDX6
Probable ATP-dependent RNA helicase DDX6

1

9

High-throughput

0.479

High

695518

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

768250

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

807431

IF4A3
Eukaryotic initiation factor 4A-III

1

11

High-throughput

0.479

High

818739

CAPG
Macrophage-capping protein

1

3

Small-scale

0.479

High

833274

PERI
Peripherin

1

17

High-throughput

0.479

High

869039

TISD
mRNA decay activator protein ZFP36L2

1

3

High-throughput

0.479

High

904741

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

942626

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.479

High

961031

MGN
Protein mago nashi homolog

1

1

High-throughput

0.479

High

970537

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.479

High

986439

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

993076

KCNJ2
Inward rectifier potassium channel 2

1

1

Small-scale

0.479

High

1094550

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

7

High-throughput

0.479

High

1126686

BECN1
Beclin-1

1

2

Small-scale

0.479

High

1144264

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1144274

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1144275

NIPBL
Nipped-B-like protein

1

18

High-throughput

0.479

High

1144283

ZN598
E3 ubiquitin-protein ligase ZNF598

1

5

High-throughput

0.479

High

1144285

SKA3
Spindle and kinetochore-associated protein 3

1

1

Small-scale

0.479

High

1144290

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1144291

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

1144293

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

2

High-throughput

0.479

High

1144294

FBXW7
F-box/WD repeat-containing protein 7

1

9

Small-scale

0.479

High

1144295

RNF31
E3 ubiquitin-protein ligase RNF31

1

9

High-throughput

0.479

High

1144296

CDCA5
Sororin

1

1

High-throughput

0.479

High

1144298

SNX27
Sorting nexin-27

1

18

High-throughput

0.479

High

1144299

CIC
Protein capicua homolog

1

13

High-throughput

0.479

High

1144302

ANM1
Protein arginine N-methyltransferase 1

1

5

High-throughput

0.479

High

1144308

TRIM6
Tripartite motif-containing protein 6

1

6

Small-scale

0.479

High

1144309

GAN
Gigaxonin

1

3

High-throughput

0.479

High

1144310

TXNIP
Thioredoxin-interacting protein

1

10

Small-scale

0.479

High

1144318

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

5

High-throughput

0.479

High

1144319

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

1144320

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

5

High-throughput

0.479

High

1144323

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1144325

FBXL4
F-box/LRR-repeat protein 4

1

3

Small-scale

0.479

High

1144327

FAF1
FAS-associated factor 1

1

3

High-throughput

0.479

High

1144331

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

1

Small-scale

0.479

High

1144333

SHLB1
Endophilin-B1

1

6

High-throughput

0.479

High

1144335

TRRAP
Transformation/transcription domain-associated protein

1

12

High-throughput

0.479

High

569106

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.458

High

587474

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

1036517

ID2
DNA-binding protein inhibitor ID-2

1

0

Small-scale

0.458

High

1144281

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1144338

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

662577

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

3

Small-scale

0.445

High

848779

MAGAA
Melanoma-associated antigen 10

1

3

High-throughput

0.445

High

966336

1433G
14-3-3 protein gamma

1

20

High-throughput

0.445

High

1103175

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

642883

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.437

High

1144271

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

1144273

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.437

High

87462

OSCRI
SCRIB overlapping open reading frame protein

1

1

High-throughput

0.407

High

653329

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.407

High

1144286

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1144269

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1144276

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.249

Low

1144287

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025