HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: JAM1 (Q9Y624)
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)
Gene: F11R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 299
+	Hs
		350737 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		1070483 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		JAM1_HUMAN (1-299): 6.01e-72: 225: 100.00
+	Hs
		350505 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		348900 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		350058 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		940426 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		348608 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		349237 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		CXAR_HUMAN (12-288): 1.06e-44: 157: 20.67
+	Hs
		349841 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		530172 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		348489 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		349096 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		NCAM1_HUMAN (16-297): 4.21e-29: 118: 14.33
+	Hs
		350572 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ROBO2_HUMAN (118-299): 2.37e-19: 90.3: 16.33
+	Hs
		350746 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		1070491 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		349043 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ROBO1_HUMAN (1-169): 2.04e-17: 84.5: 12.14
+	Hs
		507934 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		FGFR1_HUMAN (37-209): 5.59e-13: 71: 14.14
+	Hs
		350246 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97
+	Hs
		350405 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TITIN_HUMAN (24-138): 4.1e-09: 59.9: 14.66
+	Hs
		348723 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		CD276_HUMAN (33-227): 2.98e-12: 68.7: 17.97