HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 30442766, 30194290, 30655611
Identification Methods proximity labelling technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Ras
Common GO terms GO:0000139 - Golgi membrane
GO:0000165 - MAPK cascade
GO:0001934 - positive regulation of protein phosphorylation
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 189
Hs

1 189
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024