HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: MARK3 (P27448)
MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)
Gene: MARK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 753
+	Hs
		348523 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		MARK3_HUMAN (1-753): 0: 769: 100.00
+	Hs
		349893 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MARK3_HUMAN (1-753): 0: 769: 100.00
+	Hs
		647864 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		MARK3_HUMAN (1-753): 0: 769: 100.00
+	Hs
		348748 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		MARK2_HUMAN (2-753): 0: 626: 59.90
+	Hs
		350286 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MARK2_HUMAN (2-753): 0: 626: 59.90
+	Hs
		350628 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MARK1_HUMAN (1-753): 0: 619: 62.89
+	Hs
		914159 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		MARK2_HUMAN (2-753): 0: 626: 59.90
+	Hs
		349425 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		MARK2_HUMAN (2-753): 0: 626: 59.90