HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: MOB3B (Q86TA1)
MOB kinase activator 3B (Mob1 homolog 2b) (Mps one binder kinase activator-like 2B) (MOB kinase activator-like 2B)
Gene: MOB3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19739119
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 216
+	Hs
		349135 LATS1_HUMAN (1-1130): 0: 925: 100.00		MOB3C_HUMAN (1-216): 1.13e-116: 332: 71.76
+	Hs
		349195 LATS1_HUMAN (1-1130): 0: 925: 100.00		MOB3A_HUMAN (5-216): 3.02e-115: 329: 82.08
+	Hs
		349242 LATS1_HUMAN (1-1130): 0: 925: 100.00		MOB1A_HUMAN (13-214): 7.33e-109: 313: 54.46
+	Hs
		349138 LATS1_HUMAN (1-1130): 0: 925: 100.00		MOB1B_HUMAN (13-214): 6.41e-108: 310: 55.45
+	Hs
		349134 LATS1_HUMAN (1-1130): 0: 925: 100.00		MOB2_HUMAN (18-215): 7.37e-79: 237: 33.33
+	Hs
		349301 LATS1_HUMAN (1-1130): 0: 925: 100.00		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		1287074 LATS2_HUMAN (13-1121): 0: 742: 49.52		MOB3B_HUMAN (1-216): 3.21e-122: 346: 100.00
+	Hs
		1258392 LATS2_HUMAN (13-1121): 0: 742: 49.52		MOB3C_HUMAN (1-216): 1.13e-116: 332: 71.76
+	Hs
		1385124 LATS2_HUMAN (13-1121): 0: 742: 49.52		MOB3A_HUMAN (5-216): 3.02e-115: 329: 82.08
+	Hs
		1436452 LATS2_HUMAN (13-1121): 0: 742: 49.52		MOB1A_HUMAN (13-214): 7.33e-109: 313: 54.46
+	Hs
		1273131 LATS2_HUMAN (13-1121): 0: 742: 49.52		MOB1B_HUMAN (13-214): 6.41e-108: 310: 55.45
+	Hs
		1448724 LATS2_HUMAN (13-1121): 0: 742: 49.52		PHOCN_HUMAN (10-204): 1.28e-66: 206: 21.72
+	Hs
		1436461 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		MOB1A_HUMAN (13-214): 7.33e-109: 313: 54.46
+	Hs
		1273134 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		MOB1B_HUMAN (13-214): 6.41e-108: 310: 55.45
+	Xl
		1274165 Q7T0M1_XENLA (621-1098): 2.16e-161: 488: 40.00		Q7T1M9_XENLA (13-214): 6.99e-108: 310: 54.46
+	Ca
		1202857 CBK1_CANAL (448-1090): 2.59e-162: 500: 32.22		MOB2_CANAL (42-212): 7.5e-81: 245: 39.18
+	Sc
		825290 CBK1_YEAST (396-1090): 1.66e-159: 494: 30.07		MOB1_YEAST (10-214): 2.95e-82: 249: 37.38
+	Hs
		1258327 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		MOB2_HUMAN (18-215): 7.37e-79: 237: 33.33
+	Sc
		849749 CBK1_YEAST (396-1090): 1.66e-159: 494: 30.07		MOB2_YEAST (42-213): 1.14e-75: 231: 37.79
+	Sp
		149169 ORB6_SCHPO (630-1087): 6.99e-160: 484: 39.30		MOB2_SCHPO (16-214): 1.31e-76: 232: 35.18