Protein: CBK1
Serine/threonine-protein kinase CBK1 (EC 2.7.11.1) (Cell wall biosynthesis kinase)

Gene: CBK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 121
UniProt ID: P53894

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000920 - septum digestion after cytokinesis
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005628 - prospore membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636473

ACE2
Metallothionein expression activator

6

4

Small-scale

0.950

High

924413

CDC14
Tyrosine-protein phosphatase CDC14

4

9

Small-scale

0.904

High

801981

KIC1
Serine/threonine-protein kinase KIC1

3

20

Small-scale

0.841

High

924407

CBK1
Serine/threonine-protein kinase CBK1

3

15

Small-scale

0.841

High

560624

KIN1
Serine/threonine protein kinase KIN1

2

15

High-throughput

0.808

High

560743

KIN2
Serine/threonine-protein kinase KIN2

2

15

High-throughput

0.808

High

924419

STE20
Serine/threonine-protein kinase STE20

2

18

Small-scale

0.793

High

817276

ARB1
ABC transporter ATP-binding protein ARB1

2

1

Small-scale

0.767

High

849749

MOB2
CBK1 kinase activator protein MOB2

9

20

Small-scale

0.757

High

825013

TAO3
Cell morphogenesis protein PAG1

7

3

Small-scale

0.749

High

664327

SSD1
Protein SSD1

5

3

Small-scale

0.720

High

677150

LRE1
Laminarase-resistance protein LRE1

5

1

Small-scale

0.716

High

403612

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

High-throughput

0.691

High

670985

SIS1
Protein SIS1

1

8

High-throughput

0.691

High

736125

ARP2
Actin-related protein 2

1

6

High-throughput

0.691

High

817216

FIR1
Factor interacting with REF2

4

0

Small-scale

0.669

High

909755

YPT32
GTP-binding protein YPT32/YPT11

1

2

High-throughput

0.647

High

671676

SCJ1
DnaJ-related protein SCJ1

1

4

High-throughput

0.646

High

801884

KSP1
Serine/threonine-protein kinase KSP1

1

17

High-throughput

0.646

High

924410

ACT
Actin

1

5

High-throughput

0.646

High

600702

SEC2
Rab guanine nucleotide exchange factor SEC2

2

1

Small-scale

0.625

High

364678

CDK1
Cyclin-dependent kinase 1

1

11

High-throughput

0.621

High

792426

BOI1
BEM1-interacting protein 1

1

8

Small-scale

0.621

High

816036

BOI2
BEM1-interacting protein 2

1

4

Small-scale

0.621

High

579849

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.618

High

667146

CG23
G2/mitotic-specific cyclin-3

1

7

Small-scale

0.618

High

924415

LGE1
Transcriptional regulatory protein LGE1

3

0

High-throughput

0.606

High

737200

HYM1
Protein HYM1

1

0

Small-scale

0.589

High

748623

STE5
Protein STE5

1

0

Small-scale

0.589

High

924425

PAL1
Protein PAL1

2

2

High-throughput

0.586

High

817238

ZRG8
Zinc-regulated protein 8

2

0

High-throughput

0.585

High

453729

PYR1
Multifunctional protein URA2

2

5

High-throughput

0.584

High

592419

VATB
V-type proton ATPase subunit B

2

10

High-throughput

0.584

High

836830

MPG1
Mannose-1-phosphate guanyltransferase

2

2

High-throughput

0.584

High

393138

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

676233

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.575

High

737422

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

6

High-throughput

0.575

High

924408

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.575

High

510710

HSP77
Import motor subunit, mitochondrial

2

14

High-throughput

0.571

High

782306

RNZ
Ribonuclease Z

2

0

High-throughput

0.569

High

672439

STE50
Protein STE50

2

0

Small-scale

0.559

High

545819

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.552

High

825290

MOB1
DBF2 kinase activator protein MOB1

1

20

High-throughput

0.541

High

453979

IF4E
Eukaryotic translation initiation factor 4E

1

4

High-throughput

0.536

High

722150

XPO1
Exportin-1

1

9

High-throughput

0.536

High

815200

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

3

High-throughput

0.536

High

815323

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

9

High-throughput

0.536

High

816347

HSP7E
Heat shock protein SSC3, mitochondrial

1

14

High-throughput

0.536

High

825324

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

1

High-throughput

0.536

High

893281

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

7

High-throughput

0.536

High

924433

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

11

High-throughput

0.536

High

744897

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.518

High

827002

YIT6
Uncharacterized protein YIR016W

1

0

High-throughput

0.518

High

470036

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

High-throughput

0.513

High

776331

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.513

High

780048

EAP1
Protein EAP1

1

0

High-throughput

0.513

High

924431

SOG2
Leucine-rich repeat-containing protein SOG2

1

13

Small-scale

0.508

High

742918

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.501

High

386817

TBB
Tubulin beta chain

1

11

High-throughput

0.500

High

470567

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.500

High

486277

TBA1
Tubulin alpha-1 chain

1

7

High-throughput

0.500

High

924414

PRS8
26S proteasome regulatory subunit 8 homolog

1

6

High-throughput

0.500

High

479995

PRTB
Cerevisin

1

1

High-throughput

0.489

High

779786

DYHC
Dynein heavy chain, cytoplasmic

1

3

High-throughput

0.481

High

924416

SVL3
Styryl dye vacuolar localization protein 3

1

1

High-throughput

0.481

High

924423

HLR1
Protein HLR1

1

1

High-throughput

0.481

High

817452

RGI1
Respiratory growth induced protein 1

1

0

High-throughput

0.480

High

849920

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

924421

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.480

High

924430

NBA1
Protein NBA1

1

0

High-throughput

0.480

High

408336

GAL1
Galactokinase

1

0

High-throughput

0.479

High

542984

CDC24
Cell division control protein 24

1

9

High-throughput

0.479

High

679934

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

707837

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

746746

KPR1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.479

High

747979

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

826722

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

918018

PNC1
Nicotinamidase

1

2

High-throughput

0.479

High

924411

H3
Histone H3

1

8

High-throughput

0.479

High

924412

2ABA
Protein phosphatase PP2A regulatory subunit B

1

9

Small-scale

0.479

High

924422

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.479

High

924437

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

438326

NOT3
General negative regulator of transcription subunit 3

1

0

Small-scale

0.460

High

749708

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

830108

FKS2
1,3-beta-glucan synthase component GSC2

1

0

High-throughput

0.460

High

448992

TOP2
DNA topoisomerase 2

1

0

Small-scale

0.458

High

781518

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.458

High

803496

TDA3
Putative oxidoreductase TDA3

1

0

High-throughput

0.458

High

863161

FYV8
Protein FYV8

1

0

High-throughput

0.458

High

924409

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

924418

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

Small-scale

0.458

High

924420

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

924426

VID22
Vacuolar import and degradation protein 22

1

0

High-throughput

0.458

High

924428

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.458

High

924434

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

924435

CRM2
Homeostatic regulator of DAG

1

0

High-throughput

0.458

High

763246

AST1
Protein AST1

1

2

High-throughput

0.457

High

405124

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

394790

EF1A
Elongation factor 1-alpha

1

6

High-throughput

0.445

High

481716

HSP73
Heat shock protein SSA3

1

14

High-throughput

0.445

High

524774

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

527365

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

548789

MCM1
Pheromone receptor transcription factor

1

1

High-throughput

0.445

High

575984

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

597235

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.445

High

804358

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

819441

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

924427

BRE1
E3 ubiquitin-protein ligase BRE1

1

14

High-throughput

0.445

High

924436

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.445

High

776489

MPE1
Protein MPE1

1

0

High-throughput

0.438

High

812543

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

924417

YMZ2
WD repeat-containing protein YMR102C

1

5

High-throughput

0.437

High

924429

YO036
Uncharacterized protein YOL036W

2

0

Small-scale

0.320

High

735746

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.279

Low

825667

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.279

Low

826265

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.261

Low

797360

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.249

Low

917359

YGO0
Uncharacterized membrane protein YGL140C

1

0

High-throughput

0.249

Low

924424

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.249

Low

924432

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025