HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: PHLB1 (Q86UU1)
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)
Gene: PHLDB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1377
+	Hs
		348756 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		PHLB1_HUMAN (1-1377): 0: 593: 100.00
+	Hs
		350303 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		PHLB1_HUMAN (1-1377): 0: 593: 100.00
+	Hs
		350299 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		PHLB2_HUMAN (185-1376): 2.27e-103: 360: 34.71
+	Hs
		350457 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KI16B_HUMAN (14-145): 7.27e-48: 190: 37.23
+	Hs
		348944 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KI13B_HUMAN (14-257): 8.06e-42: 170: 19.76
+	Hs
		914285 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KI16B_HUMAN (14-145): 7.27e-48: 190: 37.23
+	Hs
		348594 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		AFAD_HUMAN (27-275): 2.53e-37: 155: 18.15
+	Hs
		350005 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		AFAD_HUMAN (27-275): 2.53e-37: 155: 18.15
+	Hs
		914382 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KI13B_HUMAN (14-257): 8.06e-42: 170: 19.76
+	Hs
		914346 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		KI13A_HUMAN (14-231): 7.11e-38: 157: 23.81
+	Hs
		918872 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		KIF14_HUMAN (14-232): 2.54e-35: 149: 23.66
+	Hs
		254428 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROCK2_HUMAN (591-1052): 5.68e-16: 85.9: 13.86
+	Hs
		254430 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROCK2_HUMAN (591-1052): 5.68e-16: 85.9: 13.86
+	Hs
		349927 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MYH10_HUMAN (138-864): 2.8e-15: 83.9: 7.68
+	Hs
		349926 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MYH9_HUMAN (133-878): 3.34e-14: 80.4: 9.49
+	Hs
		148636 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		CTRO_HUMAN (478-1126): 1.29e-19: 98.1: 12.89
+	Hs
		149274 RAB1B_HUMAN (4-186): 2.6e-74: 223: 31.44		CTRO_HUMAN (478-1126): 1.29e-19: 98.1: 12.89
+	Hs
		350195 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ITSN1_HUMAN (1011-1336): 6.7e-11: 69.6: 10.20
+	Hs
		254466 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ROCK2_HUMAN (591-1052): 5.68e-16: 85.9: 13.86
+	Hs
		914091 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ITSN1_HUMAN (1011-1336): 6.7e-11: 69.6: 10.20