HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0042552 - myelination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 310
+	Hs
		348900 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		JAM3_HUMAN (1-310): 3.01e-75: 234: 100.00
+	Hs
		350505 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		JAM3_HUMAN (1-310): 3.01e-75: 234: 100.00
+	Hs
		349034 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		JAM1_HUMAN (14-310): 5.99e-58: 190: 31.21
+	Hs
		350737 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		JAM1_HUMAN (14-310): 5.99e-58: 190: 31.21
+	Hs
		348608 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		349043 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		350058 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		350746 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		913999 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		914506 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		348489 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NCAM1_HUMAN (18-306): 7.35e-25: 106: 12.91
+	Hs
		348643 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		PTK7_HUMAN (31-231): 1.47e-23: 103: 16.51
+	Hs
		349841 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NCAM1_HUMAN (18-306): 7.35e-25: 106: 12.91
+	Hs
		350138 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		PTK7_HUMAN (31-231): 1.47e-23: 103: 16.51
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (134-310): 1.67e-19: 91.1: 15.71
+	Hs
		484281 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		VSIG8_HUMAN (19-264): 2.56e-30: 120: 23.21
+	Hs
		348841 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69
+	Hs
		350424 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (44-243): 7.16e-09: 59.1: 12.21
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (44-243): 7.16e-09: 59.1: 12.21