HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30442766, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression GO:0016020 - membrane GO:0044877 - protein-containing complex binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 760
+	Hs
		349051 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		348459 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364286 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364225 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364234 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364226 RAB14_HUMAN (4-184): 3.77e-72: 218: 29.51		TFR1_HUMAN (1-760): 0: 971: 100.00