HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	27684187, 30442766, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0009898 - cytoplasmic side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 904
+	Hs
		349277 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		348639 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		1021495 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		349543 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DLG3_HUMAN (139-904): 0: 585: 66.28
+	Hs
		159212 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		349319 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		348663 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		349476 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PALS1_HUMAN (1-397): 1.55e-20: 99.1: 14.74
+	Hs
		1049954 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		159130 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		1070296 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		PALS1_HUMAN (1-397): 1.55e-20: 99.1: 14.74
+	Hs
		349383 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80
+	Hs
		1070317 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		DLG5_HUMAN (202-404): 4.58e-19: 95.5: 32.02
+	Hs
		350166 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		348711 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80
+	Hs
		349246 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EM55_HUMAN (161-314): 1.14e-14: 79.5: 14.56
+	Hs
		1070233 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80
+	Hs
		348614 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		EM55_HUMAN (161-314): 1.14e-14: 79.5: 14.56
+	Hs
		350231 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80
+	Hs
		350077 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EM55_HUMAN (161-314): 1.14e-14: 79.5: 14.56