HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 30639242, 34079125
Identification Methods proximity labelling technology, far western blotting
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~Ras
Common GO terms GO:0000139 - Golgi membrane
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
and 2 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 189
Hs

1 2549
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024